Running for the 2nd time, the Mastercard Index of Women Entrepreneurs 2018 continues its focus on the progress and achievement of women entrepreneurs/business owners around the world. Using 12 indicators and 25 sub-indicators, the Index looks at how 57 economies (representing 78.6 percent of the world’s female labor force) differ in terms of the level of Women’s Advancement Outcomes, Knowledge Assets & Financial Access and Supporting Entrepreneurial Factors. The Index also provides insight on which factors and conditions are most conducive to closing the gender gap among entrepreneurs/business owners in an economy. We also look at which conditions are the biggest disablers or deterrents of women’s ability to thrive in the business world.